New overview on imaging biomarkers in OA research and drug development published by Dr. Roemer and colleagues

Biomarkers play a pivotal role in warranting the success of every stage in the drug development process, increasing the likelihood of drug candidates advancing to subsequent phases of development. Numerous innovative therapeutic approaches have been developed and currently continue to evolve to prevent or mitigate the progression of OA. The effectiveness of these techniques and their suitability for specific situations hinges on the availability of reliable diagnostic measures and biomarkers that can serve as indicators of the current or anticipated condition of cartilage and other joint tissues. Several recently emerging MRI techniques, including complementary quantitative and semiquantitative approaches,

show promise in their ability to assess longitudinal change accurately.